Regional Linkages  

Larkano is well connected with all taluka headquarters and important towns of its own district, the neighbouring districts, and the neighbouring provinces, through a network of metalled roads and railways. Following are some of the most important regional road links:

The Karachi-Quetta main railway line crosses the district on a North-South direction and connects Larkano with Sukkur and Quetta.  The same line links Larkano with Badeh, Dokri, Moenjodaro, Naudero, Dadu, Sehwan, Kotri, and Karachi.  Another line branches from Larkano and enters Jacobabad District via Shahdadkot and Qambar.

Moenjodaro airport operates regular flights from Karachi and Sukkur.  Onward connections from these two cities link Larkano with all international airports in Pakistan.  Finally, a ferry service is available in the Indus River.  This service is basically used for the transport of goods to the neighbouring districts.